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Article History

Received: 20 April 2023

Revised: 2 October 2023

Accepted: 29 October 2023

First Online: 19 December 2023

Declarations

:

: The scientific guarantor of this publication is Prof. Massimo Mischi.

: The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

: No complex statistical methods were necessary for this paper.

: All subjects (patients) provided written informed consent, indicating their willingness to be considered for future studies. This consent also covers the retrospective analysis conducted in this study.

: Institutional Review Board approval was obtained (Institutional Review Board of the Medical University of Vienna (Vienna, Austria)).

: Some of the study subjects or cohorts were previously included in the publication “Kapetas P, Clauser P, Woitek R et al (2019) Quantitative multiparametric breast ultrasound: application of contrast-enhanced ultrasound and elastography leads to an improved differentiation of benign and malignant lesions, Investigative radiology, 54:257.” This study extends the previous work by incorporating new quantitative parameters and diagnostic approaches, enhancing our ability to differentiate between benign and malignant breast lesions. While the 2019 study primarily focused on the application of contrast-enhanced ultrasound and elastography, the present study introduces original elements that distinguish it from the prior publication. Written informed consent was obtained from all subjects (patients) for their participation in this study, including retrospective analysis, and their willingness to be considered for future studies.

: • retrospective• diagnostic or prognostic study• performed at one institution