Gillespie, Ciara D. http://orcid.org/0000-0002-3006-1467
Yates, Andrew
Hughes, Mark
Ewins, Karl
McMahon, Gabriella
Hynes, John
Murphy, Mark C.
Galligan, Marie
Vencken, Sebastian
Alih, Ekele
Varden, John
Donnelly, Jennifer
Bolster, Ferdia
Rowan, Michael
Foley, Shane
NíAinle, Fionnuala
MacMahon, Peter J.
Article History
Received: 22 September 2023
Revised: 23 December 2023
Accepted: 27 December 2023
First Online: 31 January 2024
Declarations
:
: The scientific guarantor of this publication is the principal investigator Professor Peter MacMahon.
: The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.
: The UCD Clinical Research Committee kindly provided statistical advice for this manuscript and the authors include a biostatistician.
: Written informed consent was obtained from all subjects (patients) in this study.
: Institutional Review Board approval was obtained at Mater Misericordiae University Hospital, Dublin, Ireland.
: A small subset of OPTICA’s dataset (20 of 100 CTPAs) was previously analysed and reported with regard to the impact of shielding on breast dose []. This was planned as part of the study and laid out in our published protocol []. Breast shielding was not implemented in the remaining 80 CTPAs in part due to concerns regarding cross-contamination in the context of the pandemic.1. Gillespie CD, Yates A, Murphy MC, Hughes M, Ewins K, NíAinle F, Bolster F, Rowan M, Foley S, MacMahon PJ. Breast shielding combined with an optimized computed tomography pulmonary angiography pregnancy protocol: a special use-case for shielding? J Thorac Imaging 2023;38(1):36–43. .2. Gillespie C, Foley S, Rowan M, Ewins K, NiAinle F, MacMahon P. The OPTICA study (Optimised Computed Tomography Pulmonary Angiography in Pregnancy Quality and Safety study): rationale and design of a prospective trial assessing the quality and safety of an optimised CTPA protocol in pregnancy. Thrombosis research 2019;177:172–179. .
: • prospective• observational• performed at one institution.