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Article History

Received: 19 December 2023

Revised: 8 March 2024

Accepted: 10 April 2024

First Online: 31 May 2024

Compliance with ethical standards

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: The scientific guarantor of this publication is Dr. Jennifer Erley.

: The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

: Dr. Anika Buchholz from the institute of Epidemiology and Medical Biometry at the University Medical Center Hamburg-Eppendorf kindly provided statistical advice for this manuscript.

: Written informed consent was obtained from all subjects (patients) in this study.

: The study was approved by the local ethics committee of the medical association in Hamburg, Germany (Ärztekammer Hamburg, PV5131).

: Some study subjects have been previously reported in Circulation Cardiovascular Imaging by Cavus et al (Cavus E, Schneider JN, Bei der Kellen R et al (2022) Impact of Sex and Cardiovascular Risk Factors on Myocardial T1, Extracellular Volume Fraction, and T2 at 3 Tesla: Results From the Population-Based, Hamburg City Health Study. Circ Cardiovasc Imaging 15:e014158). Cavus et al investigated the effect of sex and cardiovascular risk factors on multiparametric mapping analyses in 1576 participants of the HCHS. The present study follows a different aim, which is to determine the influence of AHT, sex and the interaction between both parameters on cardiac morphology, function, and tissue characteristics. Cavus et al used different inclusion and exclusion criteria, rendering a different number and type of patients. Moreover, the statistical analyses in this study were adjusted for various confounders, which display separate independent variables in the analysis of Cavus et al Data on the differences in morphologic and functional CMR parameters between patients with arterial hypertension and controls have not been published yet to our knowledge.

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