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Authors
Stellingwerff, Menno D.
Al-Saady, Murtadha L.
Chan, Kwok-Shing
Dvorak, Adam
Marques, José P.
Kolind, Shannon
Schoenmakers, Daphne H.
van Voorst, Romy
Roosendaal, Stefan D.
Barkhof, Frederik
Wolf, Nicole I.
Berkhof, Johannes
Pouwels, Petra J. W.
van der Knaap, Marjo S. https://orcid.org/0000-0001-8912-0954
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Article History
Received: 21 March 2024
Revised: 2 July 2024
Accepted: 27 August 2024
First Online: 25 September 2024
Compliance with ethical standards
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: The scientific guarantor of this publication is M.S. van der Knaap.
: The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.
: J. Berkhof has significant statistical expertise.
: This study was approved by the local ethics committee and signed informed consent was obtained from subjects and/or caregivers.
: Institutional Review Board approval was obtained.
: Most control subjects (15 out of 16) have been previously reported (Stellingwerff et al 2023, Neuroimage). This prior article dealt with the development of the MRI acquisition protocol used in the current manuscript. The current manuscript aims to determine whether quantitative MRI measures reflect differences in neuropathology between two different leukodystrophies, correlate with clinical scores, and provide biomarkers for monitoring. These questions were not addressed in the previous article. None of the patients have been previously reported.
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