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Authors
Cai, Ying
Liu, Yang
Qiao, Huiyu
Chen, Huijun
Li, Rui
Zhang, Ji
Zhao, Xihai https://orcid.org/0000-0001-8953-0566
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (81271536, 82202108)
a grant of scientific research practice project for graduate student of specialized degree in ordinary university in Jiangsu province, China (SJLX_0621)
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Article History
Received: 18 September 2024
Revised: 21 January 2025
Accepted: 15 February 2025
First Online: 20 March 2025
Compliance with ethical standards
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: The scientific guarantor of this publication is Dr. Xihai Zhao.
: The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.
: No complex statistical methods were necessary for this paper.
: Written informed consent was obtained from all subjects (patients) in this study.
: Institutional Review Board approval was obtained.
: Some study subjects or cohorts have been previously reported in the article “Atherosclerotic plaque features and distribution in bilateral carotid arteries of the asymptomatic elderly population: a 3D multicontrast MR vessel wall imaging study,” published in the European Journal of Radiology, volume 96, pages 6–11; . The current study leverages a partially overlapping patient population from this prior work, specifically utilizing the data on carotid atherosclerotic plaque distribution features. However, the novel aspect of the current investigation lies in the addition of data on WMLs in the brain, aiming to explore the relationship between these plaque characteristics and the severity of WMLs in asymptomatic elderly individuals. The overlap in plaque distribution data allows for a more comprehensive understanding of how specific plaque features may contribute to cerebral small vessel disease, as evidenced by WMLs, in these asymptomatic elderly.
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