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Article History

Received: 16 December 2024

Revised: 11 February 2025

Accepted: 24 February 2025

First Online: 7 April 2025

Compliance with ethical standards

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: The scientific guarantor of this publication is Rossano Girometti.

: R.G. is a Deputy Editor of European Radiology, and P.C. is a member of the Scientific Editorial Board of this journal. They have not participated in the selection nor review processes for this article. The remaining authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

: Two of the authors (Maria De Martino and Miriam Isola) are biostatisticians.

: Written informed consent was waived by the Institutional Review Board because of the retrospective design.

: The study has been approved by the Institutional Review Board (IRB) of the Department of Medicine (DMED) of the University of Udine, with the approval number RIF. Prot. IRB: 263/2023.

: The study population partially overlaps with previous publications without a focus on Diffusion-weighted imaging: (1) Girometti et al []. That study included biopsy-naïve patients only and focused on different PSA-density levels to predict true positivity of prostate target biopsy. (2) Girometti et al []. In this study, we assessed which clinical and imaging variables predict the risk of false positivity of target biopsy. (3) Girometti et al []. In this study, we aimed to assess the impact on biopsy decisions of the Likert score in selectively refining the PI-RADS version 2.1 categorization.

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