Smith-Bindman, Rebecca https://orcid.org/0000-0003-1972-639X
Kang, Taewoon
Stewart, Carly
Chu, Philip W.
Wang, Yifei
Szczykutowicz, Timothy P.
Funding for this research was provided by:
National Cancer Institute (1R01CA181191-01A1)
Patient-Centered Outcomes Research Institute (CD-1304-7043)
Patient-Centered Outcomes Research Institute (DI-2018C1-11375)
Article History
Received: 22 November 2024
Revised: 12 September 2025
Accepted: 24 October 2025
First Online: 24 November 2025
Compliance with ethical standards
:
: The scientific guarantor of this publication is Dr. Rebecca Smith-Bindman.
: Dr. Smith-Bindman is a co-founder and Dr. Timothy Szczykutowicz is a consultant of Alara Imaging, Inc., a new company focused on improving the clinical and operational aspects of health systems, including collecting and reporting CT radiation dose and image quality as part of payer-led quality programs. Alara Imaging had no role in the study, and Dr. Smith-Bindman has not received funding from Alara Imaging. The other authors have no conflicts to disclose.
: Dr. Taewoon Kang performed all statistical analyses for this study, with biostatistical consultation from Mr. Philip Chu and Dr. Yifei Wang.
: The UCSF International CT Dose Registry (from which this work derived) was approved by the UCSF Institutional Review Board with a waiver of informed consent for all subjects. The waiver was approved for three reasons: the attempt to contact subjects poses a greater risk than this study; the large number of records required makes it impracticable to contact all potential subjects; and the researchers do not know the identity of the study subjects and therefore cannot contact them.
: Institutional Review Board approval was obtained.
: As these data come from a CT radiation dose registry, some of the CT exams included in this study may be represented in previous publications, including the following: (1) Smith-Bindman et al [ ]; (2) Wang et al [ ]; (3) Smith-Bindman et al [ ]; (4) Smith-Bindman et al [ ].
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