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Authors
Tang, Chun Xiang
Leipsic, Jonathon A.
Nørgaard, Bjarne L.
Gianluca, Pontone
Tesche, Christian
Yang, Junjie
Koo, Bon-Kwon
Collet, Carlos
Al-Mallah, Mouaz H.
Xu, Lei
Zhang, Jia Yin
Dai, Neng
Lu, Guang Ming
Zheng, Min Wen
Zhang, Long Jiang https://orcid.org/0000-0002-5546-6823
Schoepf, U. Joseph
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Funding
Funding for this research was provided by:
National Major Science and Technology Projects of China (2024ZD0521700)
Outstanding Youth Foundation of Jiangsu Province (BK20230048)
National Natural Science Foundation of China (82230068)
National Natural Science Foundation of China (82441019)
National Natural Science Foundation of China (82171933)
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Article History
Received: 18 May 2025
Revised: 1 December 2025
Accepted: 12 December 2025
First Online: 13 February 2026
Compliance with ethical standards
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: The scientific guarantor of this publication is Long Jiang Zhang.
: The authors of this manuscript declare relationships with the following companies: Dr. U. Joseph Schoepf receives institutional research support and honoraria for consulting and speaking from Bayer, ElucidBio, Guerbet, HeartFlow, Keya Medical, and Siemens Healthineers. Dr. Gianluca Pontone receives honoraria as speaker/consultant and/or institutional research grants from GE Healthcare, Bracco, Heartflow, Novartis, Menarini, Alexion, and Novo Nordisk. Dr. Jonathon Leipsic is a consultant to and holds stock options in HeartFlow. The other authors declare no conflicts of interest.
: No complex statistical methods were necessary for this paper.
: Written informed consent was not required for this study because the manuscript is a Special report about expert recommendations on clinical use of coronary computed tomography angiography-derived fractional flow reserve.
: Institutional Review Board approval was not required because it’s a Special report.
: Not applicable.
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