Ali Khan, Asrar http://orcid.org/0000-0001-7796-4957
Valera Vazquez, Gema http://orcid.org/0000-0001-5411-7560
Gustems, Montse http://orcid.org/0000-0003-4447-0031
Matteoni, Rafaele http://orcid.org/0000-0002-0314-5948
Song, Fei http://orcid.org/0009-0007-2626-7925
Gormanns, Philipp
Fessele, Sabine http://orcid.org/0000-0002-5399-3574
Raess, Michael http://orcid.org/0000-0002-8759-1186
Hrabĕ de Angelis, Martin http://orcid.org/0000-0002-7898-2353
,
Article History
Received: 2 May 2023
Accepted: 1 July 2023
First Online: 19 July 2023
Declarations
:
: Authors disclose that there are no financial or non-financial interests that are directly or indirectly related to the work submitted for publication.
: Disclosure of potential conflicts of interest: The authors declare that there are no potential conflicts of interests that are directly or indirectly related to this publication.
: This publication does not involve any research involving humans. It reports on research projects carried out involving the use of laboratory mice as transgenic models for human disease. The maintenance and use of transgenic mice for scientific purposes in Europe is subject to strict laws and regulations both at the national and European levels. Research reported here conform to all current European and national legislation and the participating institutions have implemented the research projects in full respect of the legal and ethical national requirements and code of practice and have endorsed the ARRIVE guidelines promoted by the National Center for Replacement, Refinement & Reduction of animals in Research (NC3Rs; ). Relevant European legislations are: The Directive 2010/63/EU regulates the welfare and protection of animals used for experimental and other scientific purposes. The EU Recommendation 2007/526 of 18 June 2007 on guidelines for the accommodation and care of animals used for experimental and other scientific purposes. The EC Regulation No 1/2005 of 22 December 2004 on the protection of animals during transport and related operations and amending Directives 64/432/EEC and 93/119/EC and Regulation (EC) No 1255/97.