Funding for this research was provided by:
National Institute of General Medical Sciences (P20PGM103395)
Article History
Received: 9 May 2025
Accepted: 6 February 2026
First Online: 24 February 2026
Declarations
:
: The authors have no conflicts of interest or competing interests.
: All animal care and use protocols were approved by the University of Alaska Fairbanks Institutional Animal Care and Use Committee (Protocol #16678882). Male Sprague–Dawley rats (Charles River Laboratories Inc., San Francisco, CA), approximately 10-weeks old, were housed in environmental chambers at 21 °C (warm) or 4 °C (cold) and a 12 h-light and 12 h-dark cycle.