Document is current

Article History

Accepted: 16 February 2025

First Online: 24 February 2025

Declarations

:

: The study was considered exempt research under 45 CFR § 46.104(d)(4) as it involved only the secondary use of data that were de-identified in compliance with the Health Insurance Portability and Accountability Act (HIPAA), specifically, 45 CFR § 164.514.

: MG, TP, WKJ, ABO, and PL are employees of Exact Sciences Corporation and own stock/stock options. JBK is an inventor of Mayo Clinic intellectual property under license to Exact Sciences and has received grant support from a sponsored research agreement between Mayo Clinic and Exact Sciences. AMF has been a consultant for AbbVie, Amgen, Centivo, Community Oncology Association, Covered California, EmblemHealth, Exact Sciences, Freedman Health, GRAIL, Harvard University, Health & Wellness Innovations, Health at Scale Technologies, MedZed, Penguin Pay, Risalto, Sempre Health, the State of Minnesota, U.S. Department of Defense, Virginia Center for Health Innovation, Wellth, and Zansors; has received research support from the Agency for Healthcare Research and Quality, Gary and Mary West Health Policy Center, Arnold Ventures, National Pharmaceutical Council, Patient-Centered Outcomes Research Institute, Pharmaceutical Research and Manufacturers of America, the Robert Wood Johnson Foundation, the State of Michigan, and the Centers for Medicare and Medicaid Services. DWE has a consulting agreement with Exact Sciences to provide support regarding research design and methodology, with proceeds paid to Mayo Clinic. MD is an Associate Professor of Medicine at Duke University and has no financial interests to disclose.