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Article History

Received: 21 May 2023

Accepted: 10 November 2023

First Online: 11 December 2023

Declarations

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: BT receives project-related funding from the German Foundation of Heart Research and Werner Otto Stiftung outside the submitted work. BT and JL share a project-related grant by the Ernst und Berta Grimmke-Stiftung. PH has received travel grants from the German Center for Cardiovascular Research (DZHK e.V.) and is supported by a grant from the Faculty of Medicine, University of Hamburg, as well as by the German Foundation of Heart Research. MK received consulting fees and honoraria from Adrenomed, Pharmacosmos, 4TEEN4, Sphingotec and Vifor Pharma. He further received grant support from Else Kroener-Fresenius foundation, German Research Foundation, European Union (Horizon 2020), Federal Ministry of Education and Research, German Center for Cardiovascular Research (DZHK e.V.), and Vifor Pharma. TZ is supported by the German Research Foundation, the EU Horizon 2020 programme, the EU ERANet and ERAPreMed Programmes, the German Center for Cardiovascular Research (DZHK e.V., 81Z0710102) and the German Ministry of Education and Research. RT reports research support from the German Center for Cardiovascular Research (DZHK e.V.), the Kühne Foundation, the Joachim Herz Foundation, the Swiss National Science Foundation (Grant No P300PB_167803) and the Swiss Heart Foundation as well as speaker honoraria/consulting honoraria from Abbott, Amgen, Astra Zeneca, Psyros, Roche, Siemens, Singulex and Thermo Scientific BRAHMS. NS receives funding by the German Heart Foundation and German Research Foundation, and reports speaker honoraria by Siemens Healthineers. DW has received honoraria from Abiomed, AstraZeneca, Bayer, Boehringer Ingelheim, Medtronic, and Novartis. JN reports honoraria from PHC, Roche and Siemens. JT, RT and TZ are listed as co-founders and shareholders of the ART-EMIS Hamburg GmbH, which holds an international patent application on the use of a computing device to estimate the probability of myocardial infarction (International Publication Numbers WO2022043229A1, TW202219980A). All other authors have reported that they have no competing risks to declare that are relevant to the content of this article.

: The study was approved by the local ethics committee Hamburg (Ethikkomission der Ärztekammer) and was conducted in accordance with the Declaration of Helsinki. All study participants provided written informed consent.