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Authors
Kadamangudi, Shrinath
Marcatti, Michela
Zhang, Wen-Ru
Fracassi, Anna
Kayed, Rakez
Limon, Agenor
Taglialatela, Giulio
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Funding
Funding for this research was provided by:
National Institutes of Health (F30AG085974, R01AG072883, R01AG072883)
University of Texas Medical Branch (Kempner Fellowship)
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Article History
Received: 11 October 2024
Revised: 22 November 2024
Accepted: 2 December 2024
First Online: 17 December 2024
Declarations
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: The authors declare that they have no financial or non-financial competing interests to disclose.
: Postmortem frozen brain tissues used in this study were obtained through established material transfer agreements with the Alzheimer’s Disease Research Center (ADRC) at Sanders-Brown Center on Aging, University of Kentucky, and the Layton Aging and Alzheimer’s Disease Center (ADC) at Oregon Health and Science University. All donors were enrolled in ongoing brain aging studies, with informed consent obtained prior to participation, and all protocols adhered to Institutional Review Board (IRB) guidelines at each institution. All donor subject samples were de-identified before being provided to the University of Texas Medical Branch (UTMB); therefore, no approval was required from the UTMB IRB per CFR §46.101(a). Animals (mice) used procure EM immunogold images were housed in adherence with USDA standards and sacrificed in compliance with UTMB’s Institutional Animal Care and Use Committee (IACUC), as well as UTMB IRB, approved protocols.
