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Authors
Alidadiani, Sara
Faura, Júlia
Wynants, Sarah
Peeters, Nele
Van den Broeck, Marleen
De Witte, Linus
Policarpo, Rafaela
Cheung, Simon
Pottier, Cyril
Ghayal, Nikhil B.
Mol, Merel O.
van Blitterswijk, Marka
Udine, Evan
DeJesus-Hernandez, Mariely
Baker, Matthew
Finch, NiCole A.
Asmann, Yan W.
van Rooij, Jeroen G. J.
Nguyen, Aivi T.
Ross Reichard, R.
Nana, Alissa L.
Lopez, Oscar L.
Boxer, Adam L.
Rosen, Howard J.
Spina, Salvatore
Herms, Jochen
Josephs, Keith A.
Petersen, Ronald C.
Rissman, Robert A.
Hiniker, Annie
Ang, Lee-Cyn
Grinberg, Lea T.
Halliday, Glenda M.
Boeve, Bradley F.
Graff-Radford, Neill R.
Seelaar, Harro
Neumann, Manuela
Kofler, Julia
White, Charles L. III
Seeley, William W.
van Swieten, John C.
Dickson, Dennis W.
Mackenzie, Ian R. A.
De Coster, Wouter
Rademakers, Rosa
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Funding
Funding for this research was provided by:
University of Antwerp (DOCPRO4)
National Institutes of Health,United States (R21NS110994)
National Institutes of Health,United States (P30AG066468)
National Institutes of Health,United States (U19AG063911)
National Institutes of Health,United States (U19AG063911)
National Institutes of Health,United States (P30AG062422)
National Institutes of Health,United States (U19AG063911)
National Institutes of Health,United States (U19AG063911)
National Institutes of Health,United States (P30AG066468)
National Institutes of Health,United States (P30AG062422)
National Institutes of Health,United States (U19AG063911)
National Institutes of Health,United States (R35NS097261)
Neuroscience Research Australia
National Health and Medical Research Council of Australia Senior Leadership Fellowship (1176607)
Canadian Institutes of Health Research (74580)
Fund for Scientific Research Flanders (12ASR24N)
The Fund Generet from the King Baudouin Foundation
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Article History
Received: 2 July 2025
Revised: 26 July 2025
Accepted: 26 July 2025
First Online: 10 August 2025
Declarations
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: Dr. Rademakers receives invention royalties from a patent related to progranulin. Dr. Mackenzie is a member of the Scientific Advisory Board of Prevail Therapeutics and receives invention royalties from a patent related to progranulin. Drs. Rademakers and De Coster are inventors on a patent filed concerning diagnostic applications in aFTLD-U.
: This study was approved by the University of Antwerp and Mayo Clinic Institutional Review Boards. The collection of tissue samples was approved by the Mayo Clinic Institutional Review Board. All autopsies were obtained after consent by the legal next-of-kin or someone legally authorized to make this decision.
