Jürgensen, Liv
Benfatto, Salvatore
Schmid, Simone
Daenekas, Bjarne
Großer, Julia
Driever, Pablo Hernáiz
Koch, Arend
Capper, David
Hovestadt, Volker
Funding for this research was provided by:
Ingeborg Rapoport Fellowship
Einstein Foundation Berlin
PLGA Fund at the Pediatric Brain Tumor Foundation
Deutsche Kinderkrebsstiftung (DKKS 2019.06, 2021.03 and 2023.08)
The Everest Centre for Research into Paediatric Low-Grade Brain Tumours (GN-000707)
Article History
Received: 9 May 2025
Revised: 5 September 2025
Accepted: 9 September 2025
First Online: 27 September 2025
Declarations
:
: D.C. and V.H. are listed as inventors on the patent ‘DNA-methylation based method for classifying tumor species’ filed by Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts and Ruprecht-Karls-Universität Heidelberg. D.C. is a shareholder and co-founder of Heidelberg Epignostix GmbH. P.H.D. is a member of the Alexion Advisory Board on behalf of Charité-Universitätsmedizin Berlin. The remaining authors declare no competing interests.
: The protocol of the HIT-LOGGIC-Registry was approved by the IRB (EA2/030/19). Approvals for the LOGGIC Core protocol (and any modifications thereof) were obtained from independent ethics committees and the institutional review board at each participating center. The study was registered with the German Clinical Trial Register (DRKS00019035).