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Authors
Tsafaras, George
Cabezudo, Diego
Wetzels, Lot
Tsakogias, Iraklis
Abey, Ajantha
Bentea, Eduard
Sanchiz-Calvo, Maria
Van den Haute, Chris
Wade-Martins, Richard
Baekelandt, Veerle
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Funding
Funding for this research was provided by:
Fonds Wetenschappelijk Onderzoek
Parkinson's UK
Medical Research Council Centre for Neurodevelopmental Disorders
KU Leuven (C14/18/102)
Michael J. Fox Foundation for Parkinson's Research
Queen Elisabeth Medical Foundation
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Article History
Received: 18 July 2025
Revised: 29 October 2025
Accepted: 30 October 2025
First Online: 11 November 2025
Declarations
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: All animal experiments were carried out in accordance with the European Communities Council Directive of November 24, 1986 (86/609/EEC) and approved by the Bioethical Committee of the KU Leuven (Belgium) (ECD projects 051/2020 and 156/2022). Participants were recruited to the Discovery clinical cohort through the Oxford Parkinson’s Disease Center and gave signed informed consent to mutation screening and derivation of iPSC lines from skin biopsies (Ethics committee: National Health Service, Health Research Authority, NRES Committee South Central, Berkshire, UK, REC 10/H0505/71).
: The authors consent to the publication. Manuscript was read and approved by all authors.
: All data generated or analyzed during this study is included in this published article [and its supplementary information files].
: The authors declare that they have no competing interests.
