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Article History

Received: 7 April 2025

Revised: 9 October 2025

Accepted: 11 February 2026

First Online: 28 February 2026

Declarations

:

: The authors declare no competing interests.

: All mouse experiments were conducted in accordance with protocols approved by the Ethics Committee of Animal Care and Use. The Lab of Animal Experimental Ethical Inspection of Dr.Can Biotechnology (Zhejiang) Co.,Ltd. (Zhejiang, China; Approval number: DRK2024092701). The animal experiments complied with the National Institute of Health’s Guide for the Care and Use of Laboratory Animals (NIH Publications no. 8023, revised in 1978).

: During the preparation of the manuscript, the authors used Perplexity AI to enhance the readability and clarity of the text, as well as to reduce grammatical errors. This tool assisted in ensuring that the manuscript’s statements were presented clearly and understandably, facilitating better communication of the research findings. After using this tool, the authors reviewed and edited the content as needed and take full responsibility for the content of the publication.