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False-positive rates in screening for trisomies 18 and 13: a comparison between first-trimester combined screening and a cfDNA-based approach

Crossref DOI link: https://doi.org/10.1007/s00404-018-4983-2

Published Online: 2018-12-05

Published Print: 2019-02

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Kagan, Karl Oliver https://orcid.org/0000-0003-1497-5143
Sonek, Jiri

Sroka, Andreas

Abele, Harald

Wagner, Philipp

Prodan, Natalia

Hoopmann, Markus
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Article History

Received: 20 July 2018

Accepted: 17 November 2018

First Online: 5 December 2018

Compliance with ethical standards

:

: All authors declare that they have no conflict of interest.

: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This is a secondary analysis of a randomized controlled study at the University of Tübingen. Approval for the prospective study was obtained from the local ethics committee (no. 572/2015BO1). The original study was registered in the International Standard Randomized Controlled Trial Number registry (ISRCTN no. 11174071). Approval for the retrospective study was also obtained from the local ethics committee (no. 531/2018BO2).