Lieb, Anne https://orcid.org/0009-0002-0460-172X
Zrenner, Brigitte
Becker-Sadzio, Julia
Gordon, Pedro Caldana
Kozák, Gábor
Zrenner, Christoph
Martus, Peter
Ziemann, Ulf
Fallgatter, Andreas
Clinical trials referenced in this document:
Documents that mention this clinical trial
Brain oscillation-synchronized stimulation for major depression: a randomized controlled trial comparing EEG-triggered repetitive TMS with standard iTBS (Acronym: BOSSFRONT2)
https://doi.org/10.1007/s00406-025-02176-9
Funding for this research was provided by:
Universitätsklinikum Tübingen
Article History
Received: 3 March 2025
Accepted: 9 December 2025
First Online: 21 January 2026
Declarations
:
: UZ received grants from the European Research Council (ERC), the German Ministry of Education and Research (BMBF) and the German Research Foundation (DFG), and consulting fees from CorTec GmbH, all not related to this work. AJF received grants from the German Ministry of Education and Research (BMBF) and the German Research Foundation (DFG), all not related to the current work. PM received grants from the German Ministry of Education and Research (BMBF) and the German Research Foundation (DFG), all not related to the current work. CZ, BZ and GK declare an interest in the sync2brain GmbH, Tübingen, Germany, a spin-off start-up company that was formed to commercialize the real-time EEG analysis technology used in this study. The other authors declare that they have no competing interests.
: The study was approved on November 7, 2022 by this ethics committee under project number 529/2019BO1 (see Appendix for approval documents). The study will be conducted in accord with the latest version of the declaration of Helsinki and in accord with the professional code of conduct. Please see the additional files for the original ethical approval and the English translation.
: Not applicable. This study protocol manuscript does not contain any identifiable individual data.
: Written informed consent will be obtained from all participants or, respectively, their representatives prior to study enrollment.