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Article History

Received: 30 January 2025

Accepted: 16 April 2025

First Online: 6 May 2025

Declarations

:

: JZ received fees for presentation at symposia and or publications from Angelini CZ, AstraZeneca CZ, Sanofi CZ, GlaxoSmithKline CZ, received fees for advisory board participation from Berlin-Chemie CZ, AstraZeneca CZ, Sanofi CZ, GlaxoSmithKline CZ and reports travel grant from Angelini CZ. All above mentioned is outside the submitted work. CP received fees for presentation at symposia from Recipharm and Eurodrug; received fees for Advisory Board participation from Recipharm, Eurodrug, MicroA, EpiEndo and Ananda Developments; received fees as a Non Executive Director of Ananda Developments. VK reports non-financial support from Meditech Media, UK, Boehringer Ingelheim RCV Vienna, AUT, Charles University, Czechia, and Ministry of the Health, Czechia, during the conduct of the study. He gave presentations at symposia and sponsored and received fees for advisory board participation and travel grants from Angelini, AstraZeneca, Berlin-Chemie CZ, Boehringer Ingelheim CZ, Chiesi CZ and Menarini IL. He received research grants from Angelini CZ, AstraZeneca CZ, Boehringer Ingelheim CZ, RCV, and Chiesi CZ. Moreover, VK received an honorarium from the Roche Europe advisory board and Sanofi CZ advisory board. All above mentioned is outside the submitted work. KB reports non-financial support from Angelini CZ and Ministry of the Health, Czechia, during the study, sponsored presentations at congresses and symposia and fees for advisory boards from Chiesi CZ, Angelini CZ, AstraZeneca CZ, Sanofi CZ and Menarini. All the above are outside the submitted work. EV has received COPD research funding/travel grants from AstraZeneca CZ and consulting/lectures/advisory board payment from AstraZeneca CZ, GlaxoSmithKline CZ and Sanofi CZ. MP received fees for presentation at symposia from AstraZeneca CZ, fees for advisory board participation from GlaxoSmithKline CZ. All above mentioned is outside the submitted work. MS and MK have nothing to disclose.

: This observational study was conducted in accordance with the laws of the Czech Republic and the ethical principles of the Declaration of Helsinki. Institutional Multicenter Ethic Committee of University Hospital Hradec Kralove (Charles University, Czechia, EU) approved study protocol with informed consent on 12 February 2013; approval number 201303 501P.

: All participants provided written consent prior to enrollment on the Czech Multicenter Research Database of COPD.