Lim, Charmaine J. M.
Wouters, Emiel F. M.
Mraz, Tobias L.
Irvin, Charles G.
Breyer, Marie-Kathrin
Breyer-Kohansal, Robab
Article History
Received: 19 December 2025
Accepted: 27 February 2026
First Online: 14 March 2026
Declarations
:
: The authors declare no competing interests.
: No clinical trial number is applicable to this study. This study was conducted within the framework of the LEAD study which has been approved by the local Ethics committee of Vienna (EK-11-117-0711) with the project identification code, NCT017257518 (ClinicalTrials.gov) in accordance with the Declaration of Helsinki. No ethics approval was required pertaining to the manuscript.
: Written informed consent was obtained from all individual participants included in the LEAD study. Further consent for this study was not applicable.