Funding for this research was provided by:
Japan Society for the Promotion of Science (16H05583, 25293449, 16H03044)
Text and Data Mining valid from 2019-03-13
Received: 18 January 2019
Revised: 28 February 2019
Accepted: 7 March 2019
First Online: 13 March 2019
Compliance with ethical standards
: Dr. Shimizu reports speaker honoraria from Tanabe Mitsubishi Pharma. The other authors declare that they have no conflict of interest.
: The study was approved by the ethics committee at Tokyo Metropolitan Neurological Hospital (TS-H29-048). All patients provided informed consent to participate in the study, in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.