Funding for this research was provided by:
Ministero della Salute (GR-2011-02351217)
Text and Data Mining valid from 2019-03-29
Received: 13 March 2019
Revised: 22 March 2019
Accepted: 23 March 2019
First Online: 29 March 2019
Compliance with ethical standards
: E. Canu has received research supports from the Italian Ministry of Health. M. Leocadi, V. Bessi, S. Padiglioni, B. Nacmias, S. Sorbi report no disclosures. M. Filippi is Editor-in-Chief of the Journal of Neurology; has received compensation for consulting services and/or speaking activities from Biogen Idec, Merck Serono, Novartis, and Teva Pharmaceutical Industries; and receives research support from Biogen Idec, Teva Pharmaceutical Industries, Novartis, Merck Serono, Roche, Italian Ministry of Health, Fondazione Italiana Sclerosi Multipla, and ARiSLA (Fondazione Italiana di Ricerca per la SLA). F. Agosta is Section Editor of NeuroImage: Clinical; has received speaker honoraria from Biogen Idec and Novartis; and receives or has received research supports from the Italian Ministry of Health, AriSLA (Fondazione Italiana di Ricerca per la SLA), and the European Research Council.
: This study has been approved by the local ethics committee and has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. The patient gave her informed consent prior to their inclusion in the study.