Freedman, Mark S. http://orcid.org/0000-0003-1255-9701
Brod, Staley
Singer, Barry A.
Cohen, Bruce A.
Hayward, Brooke
Dangond, Fernando
Coyle, Patricia K.
Funding for this research was provided by:
EMD Serono
Pfizer Foundation
Article History
Received: 29 March 2019
Revised: 6 September 2019
Accepted: 7 September 2019
First Online: 26 September 2019
Compliance with ethical standards
:
: MSF has received honoraria or consulting fees from Actelion, Bayer HealthCare, Biogen, Chugai, EMD Canada, Genzyme, Hoffmann-La Roche, Merck Serono, Novartis, Sanofi-Aventis, and Teva Canada Innovation; has served on an advisory boards for Actelion, Bayer HealthCare, Biogen, Hoffmann-La Roche, Merck Serono, Novartis, Opexa, and Sanofi-Aventis; and has participated in a speakers’ bureau for Genzyme. SB has consulting agreements or has received speaker honoraria from Acorda, Avanir, Bayer HealthCare, EMD Serono, Genzyme, Pfizer, Questcor, and Teva Neurosciences; has served on advisory boards for Bayer HealthCare, EMD Serono, Genzyme, Questcor, Sanofi, and Teva; and has received research or contractual support from the Clayton Foundation for Research, EMD Serono, Pfizer, and Questcor. BAS has received consulting and/or speaking fees from Acorda, Bayer, Biogen, EMD Serono, Genentech, Novartis, Roche, Sanofi Genzyme, and Teva; and has received research/grant support from Acorda, Biogen, Genzyme, MedImmune, Novartis, and Roche. BAC has received consulting fees from Biogen-Idec, Celgene, and EMD Serono; and contracted research support through Northwestern University from EMD Serono, Hoffman-La Roche/Genentech, MedDay, and Novartis. BH is an employee of EMD Serono, Inc., Rockland, MA, USA. FD is an employee of EMD Serono, Inc., Billerica, MA, USA. PKC has received consulting fees from Accordant, Bayer, Biogen, Celgene, EMD Serono, Genentech/Roche, Genzyme/Sanofi, and Novartis; and has received fees for contracted research with Actelion, Alkermes, Genzyme/Sanofi, MedDay, National Institute of Neurological Disorders and Stroke (NINDS), and Novartis.
: In the PRISMS and SPECTRIMS studies, all patients provided written informed consent prior to treatment. Both studies were conducted in accordance with the ethical principles set forth in the Declaration of Helsinki and standards for Good Clinical Practice.