Document is current

Article History

Received: 3 July 2021

Revised: 15 October 2021

Accepted: 17 October 2021

First Online: 29 October 2021

Declarations

:

: Tom Fuchs, Tommy Broeders, Jacob Silver, and Dejan Jakimovski have nothing to declare. Menno Schoonheim serves on the editorial board of Frontiers of Neurology and has received research support, compensation for consulting services or speaker honoraria from the Dutch MS Research Foundation, ARSEP, Eurostars-EUREKA, ZonMW, ExceMed, Amsterdam Neuroscience, Atara, Biogen, Celgene/BMS, Merck, MedDay and Sanofi-Genzyme. Hanneke E. Hulst serves in the editorial board of MSJ and has received compensation for consulting services or speaker honoraria from Sanofi Genzyme, Biogen Idec, Celgene, and Merck. BV. Bianca Weinstock-Guttman received honoraria as a speaker and as a consultant for Biogen Idec, Teva Pharmaceuticals, EMD Serono, Genzyme, Sanofi, Novartis and Acorda. Dr Weinstock-Guttman received research funds from Biogen Idec, Teva Pharmaceuticals, EMD Serono, Genzyme, Sanofi, Novartis, and Acorda. Robert Zivadinov received personal compensation from EMD Serono, Sanofi, Novartis, Bristol Myers Squibb, and Keystone Heart for speaking and consultant fees. He received financial support for research activities from Sanofi, Novartis, Bristol Myers Squibb, Mapi Pharma, Keystone Heart, V-VAWE Medical, Boston Scientific and Protembo. Jeroen Geurts is an editor of Multiple Sclerosis Journal and is president of the Netherlands organization for health research and innovation. He has received research support or compensation for consulting services from the Dutch MS Research Foundation, Ammodo, Eurostars-EUREKA, Biogen, Celgene/BMS, Merck, MedDay, Novartis and Sanofi-Genzyme. Michael G. Dwyer has received consultant fees from Claret Medical and EMD Serono and research Grant support from Novartis. Ralph HB Benedict receives research support from Biogen, Bristol Meyers Squibb, Genzyme, Genentech, Novartis, National Institutes of Health, National Multiple Sclerosis Society, and Verasci. Dr. Benedict has received compensation for speaking and consulting services from Immunic Therapeutics, Latin American Committee for Treatment and Research in Multiple Sclerosis, Merck, Novartis, Roche, Sanofi, Biogen, Bristol Meyers Squibb, and EMD Serono, and receives royalties from Psychological Assessment Resources.

: The study protocol was approved by the University at Buffalo Institutional Ethics Review Board.

: All subjects provided written informed consent before participation.