Tavazzi, Erica
Daberdaku, Sebastian
Zandonà, Alessandro
Vasta, Rosario
Nefussy, Beatrice
Lunetta, Christian
Mora, Gabriele
Mandrioli, Jessica
Grisan, Enrico
Tarlarini, Claudia
Calvo, Andrea
Moglia, Cristina
Drory, Vivian
Gotkine, Marc
Chiò, Adriano
Di Camillo, Barbara http://orcid.org/0000-0001-8415-4688
Chiò, A.
Montalcini, Rita Levi
Calvo, A.
Moglia, C.
Canosa, A.
Manera, U.
Vasta, R.
Palumbo, F.
Bombaci, A.
Grassano, M.
Brunetti, M.
Casale, F.
Fuda, G.
Salomone, P.
Iazzolino, B.
Peotta, L.
Cugnasco, P.
De Marco, G.
Torrieri, M. C.
Gallone, S.
Barberis, M.
Sbaiz, L.
Gentile, S.
Mauro, A.
Mazzini, L.
Marchi, F.
Corrado, L.
D’Alfonso, S.
Bertolotto, A.
Gionco, M.
Leotta, D.
Oddenino, E.
Cavallo, R.
De Mattei, M.
Gusmaroli, G.
Comi, C.
Labate, C.
Poglio, F.
Ruiz, L.
Ferrandi, D.
Testa, L.
Rota, E.
Aguggia, M.
Di Vito, N.
Meineri, P.
Ghiglione, P.
Launaro, N.
Dotta, M.
Sapio, A.
Giovanni, M.
Mandrioli, J.
Mandrioli, J.
Fini, N.
Martinelli, I.
Zucchi, E.
Gianferrari, G.
Simonini, C.
Vinceti, M.
Meletti, S.
Vacchiano, V.
Liguori, R.
Salvi, Fabrizio
Bartolomei, Ilaria
Michelucci, Roberto
Cortelli, P.
Borghi, A. M.
Zini, A.
Rinaldi, R.
Cortelli, P.
Sette, E.
Tugnoli, V.
Pugliatti, M.
Canali, E.
Codeluppi, L.
Valzania, F.
Zinno, L.
Pavesi, G.
Medici, D.
Pilurzi, G.
Terlizzi, E.
Guidetti, D.
Pasqua, S.
Santangelo, M.
Bracaglia, M.
DeMassis, P.
Casmiro, M.
Querzani, P.
Morresi, S.
Longoni, M.
Patuelli, A.
Malagù, S.
Longoni, M.
Currò Dossi, M.
Vidale, S.
,
Funding for this research was provided by:
Regione Emilia-Romagna (ERRALS register grant)
Seventh Framework Programme (259867)
Ministero dell’Istruzione, dell’Università e della Ricerca ("Departments of Excellence" (Law 232/2016), PRIN, grant 2017SNW5MB)
Ministero degli Affari Esteri e della Cooperazione Internazionale (CompALS project)
Ministero della Salute (Ricerca Sanitaria Finalizzata, grant RF-2016-02362)
Ministry of Science, Technology and Space of the State of Israel (CompALS project)
Article History
Received: 10 September 2021
Revised: 9 February 2022
Accepted: 9 February 2022
First Online: 10 March 2022
Change Date: 4 August 2022
Change Type: Update
Change Details: Missing Open Access funding information has been added in the Funding Note
Declarations
:
: Dr. Chiò reports personal fees from Biogen, personal fees from Amylyx, personal fees from Denali, outside the submitted work. Dr. Di Camillo reports grants from The Italian Ministry of Foreign Affairs and International Cooperation, grants from the Ministry of Science, Technology and Space of the State of Israel, during the conduct of the study; grants from Italian Ministry of Health (Ministero della Salute), outside the submitted work. Dr. Drory reports grants from the Israel Ministry of Science, Technology and Space, during the conduct of the study. Dr. Grisan reports grants from The Italian Ministry of Foreign Affairs and International Cooperation, grants from the Ministry of Science, Technology and Space of the State of Israel, during the conduct of the study; personal fees from GE Healthcare, grants from Italian Ministry of Education, University and Research—PRIN, grants from Ministry of Health—Applied Research, outside the submitted work. Dr. Lunetta reports personal fees from Italfarmaco, personal fees from Mitsubishi Tanabe Pharma Europe, personal fees from Cytokinetics, outside the submitted work. Dr. Mandrioli reports grants from Emilia Romagna Regional Health Authority, during the conduct of the study. Dr. Beatrice Nafussy reports grants from the Ministry of Science, Technology and Space of the State of Israel during the conduct of the study. Dr. Zandonà reports grants from The Italian Ministry of Foreign Affairs and International Cooperation, grants from the Ministry of Science, Technology and Space of the State of Israel, during the conduct of the study. The tool presented in this paper was patented on 22 July 2020 as PCT/IT2020/000057: “Method for determining the prognosis of disease progression and survival for patients affected by Amyotrophic Lateral Sclerosis”, Di Camillo B, Zandonà A, Daberdaku S, Tavazzi E, Chiò A, Vasta R, Calvo A, Moglia C, Casale F, D’Ovidio F, Mandrioli J, Lunetta C, Drory V, Mora G, and Gotkine M. No other competing interests declared.
: The study was approved by the ethical committees of the coordinating and participating centres (clinical study coordinator: Centro Clinico NEMO, Fondazione Serena ONLUS, Milano). Written informed consent to participate in the study was obtained from all the patients or their legal representatives. Data were anonymised according to the privacy protection legislation of Italy and Israel. All study protocols and procedures were conducted in accordance with the Declaration of Helsinki.
: Informed consent to participate in the study was obtained from all the patients or their legal representatives.