Li, Ying
Saul, Alice
Taylor, Bruce
Ponsonby, Anne-Louise
Simpson-Yap, Steve
Blizzard, Leigh
Broadley, Simon
Lechner-Scott, Jeannette
Lucas, Robyn
Dear, Keith
Ponsonby, Anne-Louise
Dwyer, Terry
van der Mei, Ingrid
Blizzard, Leigh
Simpson-Yap, Steve
Taylor, Bruce
Broadley, Simon
Kilpatrick, Trevor
Williams, David
Lechner-Scott, Jeanette
Shaw, Cameron
Chapman, Caron
Coulthard, Alan
Pender, Michael
Valery, Patricia
Karabudak, Rana
Patti, Francesco
Eichau, Sara
Onofrj, Marco
Ozakbas, Serkan
Horakova, Dana
Kubala Havrdova, Eva
Grand’Maison, Francois
Alroughani, Raed
Gerlach, Oliver
Amato, Maria Pia
Altintas, Ayse
Girard, Marc
Duquette, Pierre
Blanco, Yolanda
Ramo-Tello, Cristina
Laureys, Guy
Kalincik, Tomas
Khoury, Samia J.
Shaygannejad, Vahid
Etemadifar, Masoud
Singhal, Bhim
Mrabet, Saloua
Foschi, Matteo
Habek, Mario
John, Nevin
Hughes, Stella
McCombe, Pamela
Ampapa, Radek
van der Walt, Anneke
Butzkueven, Helmut
de Gans, Koen
McGuigan, Chris
Oreja-Guevara, Celia
Sa, Maria Jose
Petersen, Thor
Al-Harbi, Talal
Sempere, Angel Perez
Van Wijmeersch, Bart
Grigoriadis, Nikolaos
Prevost, Julie
Gray, Orla
Castillo-Triviño, Tamara
Macdonell, Richard
Lugaresi, Alessandra
Sajedi, Seyed Aidin
Karabudak, Rana
Patti, Francesco
Eichau, Sara
Onofrj, Marco
Ozakbas, Serkan
Horakova, Dana
Kubala Havrdova, Eva
Grand’Maison, Francois
Alroughani, Raed
Gerlach, Oliver
Amato, Maria Pia
Altintas, Ayse
Girard, Marc
Duquette, Pierre
Blanco, Yolanda
Ramo-Tello, Cristina
Laureys, Guy
Kalincik, Tomas
Khoury, Samia J.
Shaygannejad, Vahid
Etemadifar, Masoud
Singhal, Bhim
Mrabet, Saloua
Foschi, Matteo
Habek, Mario
John, Nevin
Hughes, Stella
McCombe, Pamela
Ampapa, Radek
van der Walt, Anneke
Butzkueven, Helmut
de Gans, Koen
McGuigan, Chris
Oreja-Guevara, Celia
Sa, Maria Jose
Petersen, Thor
Al-Harbi, Talal
Sempere, Angel Perez
Van Wijmeersch, Bart
Grigoriadis, Nikolaos
Prevost, Julie
Gray, Orla
Castillo-Triviño, Tamara
Macdonell, Richard
Lugaresi, Alessandra
Sajedi, Seyed Aidin
Campbell, Jamie
Zwanikken, Cees
van Pesch, Vincent
Izquierdo, Guillermo
Maimone, Davide
Weinstock-Guttman, Bianca
Terzi, Murat
Prat, Alexandre
Boz, Cavit
Zakaria, Magd
van Hijfte, Liesbeth
Yamout, Bassem
Grammond, Pierre
Rojas, Juan Ignacio
Spitaleri, Daniele
Lechner-Scott, Jeannette
Buzzard, Katherine
Skibina, Olga
Shalaby, Nevin
Gouider, Riadh
Cristiano, Edgardo
Kuhle, Jens
Slee, Mark
Turkoglu, Recai
Sinnige, L. G. F.
Sanchez-Menoyo, Jose Luis
Solaro, Claudio
Cartechini, Elisabetta
Iuliano, Gerardo
Taylor, Bruce
Talaat, Farouk
Barnett, Michael
Oh, Jiwon
Rio, Maria Edite
Fernandez-Bolaños, Ricardo
Khurana, Dheeraj
Besora, Sarah
Soysal, Aysun
Saladino, Maria Laura
Den Braber-Moerland, Leontien
Cabrera-Gomez, Jose Antonio
Willekens, Barbara
Garber, Justin
Brola, Waldemar
Fragoso, Yara
Al-Asmi, Abdullah
Kermode, Allan
Fabis-Pedrini, Marzena
Lapointe, Emmanuelle
Hodgkinson, Suzanne
Vasconcelos, Claudia
Lalive, Patrice
Shaw, Cameron
Gobbi, Claudio
Shalaby, Nevin
Cardenas-Robledo, Simon
Hardy, Todd
Bacile, Elizabeth Alejandra
Pucci, Eugenio
Parratt, John
Baghbanian, Seyed Mohammad
Vrech, Carlos
Field, Deborah
Kister, Ilya
Schepel, Jan
Joseph, Joyce Pauline
Cambron, Melissa
Deri, Norma
Sirbu, Carmen-Adella
Moore, Fraser
Tsolaki, Magda
Boggild, Mike
Tsai, Nai-Wen
Shuey, Neil
Flechter, Shlomo
Mihaela, Simu
Jimenez, Alejandro Jose Diaz
Quek, Chu Zhen
Decoo, Danny
Karussis, Dimitrios
Aguera-Morales, Eduardo
Roullet, Etienne
Tan, Ik Lin
Alkhaboori, Jabir
Inshasi, Jihad
Kotkata, Karim
Gross-Paju, Katrin
Simo, Magdolna
Al Khawajah, Mona
Razazian, Nazanin
Charest, Stephane
Csepany, Tunde
Santiago, Vetere
Liu, Yaou
van der Mei, Ingrid
,
,
Funding for this research was provided by:
Multiple Sclerosis Australia (14-031)
University of Tasmania
Article History
Received: 18 April 2023
Revised: 28 August 2023
Accepted: 29 August 2023
First Online: 28 September 2023
Declarations
:
: Francesco Patti received personal compensation for serving on advisory board by Almirall, Alexion, Biogen, Bristol, Berck, Novartis and Roche, and further received research grant by Biogen, Merck and Roche and by FISM, Reload Association (Onlus), Italian Health Minister, University of Catania. Sara Eichau received speaker honoraria and consultant fees from Biogen Idec, Novartis, Merck, Bayer, Sanofi Genzyme, Roche and Teva. Dana Horakova received compensation for travel, speaker honoraria and consultant fees from Biogen, Novartis, Merck Healthcare KGaA (Darmstadt, Germany), Bayer, Sanofi, Roche, and Teva, as well as support for research activities from Biogen. She was also supported by the Charles University: Cooperatio Program in neuroscience. Eva Kubala Havrdova received honoraria/research support from Biogen, Merck Serono, Novars, Roche, and Teva; has been member of advisory boards for Actelion, Biogen, Celgene, Merck Serono, Novars, and Sanofi Genzyme. Francois Grand'Maison received honoraria or research funding from Biogen, Genzyme, Novartis, Teva Neurosciences, and ATARA Pharmaceuticals. Raed Alroughani received honoraria as a speaker and for serving on scientific advisory boards from Bayer, Biogen, GSK, Merck, Novartis, Roche and Sanofi-Genzyme. Maria Pia Amato received honoraria as consultant on scientific advisory boards by Biogen, Bayer-Schering, Merck, Teva and Sanofi-Aventis; has received research grants by Biogen, Bayer-Schering, Merck, Teva and Novartis. Ayse Altintas received speaker honoraria from Merck, Alexion; received travel and registration grants from Merck. Pierre Duquette served on editorial boards and has been supported to attend meetings by EMD, Biogen, Novartis, Genzyme, and TEVA Neuroscience. He holds grants from the CIHR and the MS Society of Canada and has received funding for investigator-initiated trials from Biogen, Novartis, and Genzyme. Yolanda Blanco received speaker honoraira from Merck, Biogen, Brystol, Novartis and Sanofi. Cristina Ramo-Tello received research funding, compensation for travel or speaker honoraria from Biogen, Novartis, Bristol, Janssen, Sanofi, Merck and Almirall. Guy Laureys received travel and/or consultancy compensation from Sanofi-Genzyme, Roche, Teva, Merck, Novartis, Celgene, Biogen. Tomas Kalincik served on scientific advisory boards for MS International Federation and World Health Organization, BMS, Roche, Janssen, Sanofi Genzyme, Novartis, Merck and Biogen, steering committee for Brain Atrophy Initiative by Sanofi Genzyme, received conference travel support and/or speaker honoraria from WebMD Global, Eisai, Novartis, Biogen, Roche, Sanofi-Genzyme, Teva, BioCSL and Merck and received research or educational event support from Biogen, Novartis, Genzyme, Roche, Celgene and Merck. Samia J. Khoury received compensation for scientific advisory board activity from Merck and Roche. Bhim Singhal received consultancy honoraria and compensation for travel from Biogen and Merck. Saloua Mrabet has received a MENACTRIMS clinical fellowship grant (2020). Nevin John NAJ is a local principal investigator on commercial studies funded by Novartis, Biogen, Amicus and Sanofi. Stella Hughes has received unrestricted educational grants or speaking honoraria from Biogen, Merck Serono, Novartis, Roche and Sanofi Genzyme. Pamela McCombe received honoraria and consulting fees from Novartis, Bayer Schering and Sanofi and travel grants from Novartis, Biogen and Bayer Schering. Received speakers fees and travel grants from Novartis, Biogen, T’évalua, Sanofi. Radek Ampapa received conference travel support from Novartis, Teva, Biogen, Bayer and Merck and has participated in a clinical trials by Biogen, Novartis, Teva and Actelion. Anneke van der Walt served on advisory boards and receives unrestricted research grants from Novartis, Biogen, Merck and Roche She has received speaker’s honoraria and travel support from Novartis, Roche, and Merck. She receives grant support from the National Health and Medical Research Council of Australia and MS Research Australia. Helmut Butzkueven received institutional (Monash University) funding from Biogen, F. Hoffmann-La Roche Ltd, Merck, Alexion, CSL, and Novartis; has carried out contracted research for Novartis, Merck, F. Hoffmann-La Roche Ltd and Biogen; has taken part in speakers’ bureaus for Biogen, Genzyme, UCB, Novartis, F. Hoffmann-La Roche Ltd and Merck; has received personal compensation from Oxford Health Policy Forum for the Brain Health Steering Committee. Koen de Gans served on scientific advisory boards for Roche, Janssen, Sanofi-Genzyme, Novartis and Merck, received conference fee and travel support from Novartis, Biogen, Sanofi-Genzyme, Teva, Abbvie and Merck and received educational event support from Novartis. Chris McGuigan received honoraria/research funding from Biogen, BMS, Jannsen, Merck, Novartis & Roche. Celia Oreja-Guevara received honoraria as consultant on scientific advisory boards from Biogen, Celgene, Merck, Novartis, Roche, Sanofi-Genzyme and TEVA. Maria Jose Sa received consulting fees, speaker honoraria, and/or travel expenses for scientific meetings from Alexion, Bayer Healthcare, Biogen, Bristol Myers Squibb, Celgene, Janssen, Merck-Serono, Novartis, Roche, Sanofi and Teva. Thor Petersen received funding from Biogen, Merck, Novartis, Sanofi-Aventis, Roche, and Genzyme. Angel Perez sempere received honoraria as consultant on scientific advisory boards from Biogen, Merck, Novartis, Roche and TEVA. Bart Van Wijmeersch received research and travel grants, honoraria for MS-Expert advisor and Speaker fees from Almirall, Biogen, BMS, Imcyse, Janssen, Sanofi, Merck, Novartis, Roche and Teva. Nikolaos Grigoriadis travel support and/or honoraria and/or research grants and/or lecture fees and/or advisory services and/or consulting fees from Novartis, Bayer, Merck, Genesis, Sanofi, Specifar, Roche, Biogen, Teva, Mylan, Merck Serono, Sanofi Genzyme, Celgene, and ELPEN. Julie Prevost accepted travel compensation from Novartis, Biogen, Genzyme, Teva, and speaking honoraria from Biogen, Novartis, Genzyme and Teva. Orla Gray received honoraria as consultant on scientific advisory boards for Genzyme, Biogen, Merck, Roche, and Novartis; has received travel grants from Biogen, Merck, Roche, and Novartis; has participated in clinical trials by Biogen and Merck. She has received research grant support from Biogen. Tamara Castillo Triviño received speaking/consulting fees and/or travel funding from Almirall, Biogen, Bristol Myers Squibb, Janssen, Merck, Novartis, Roche and Sanofi-Genzyme. Richard Macdonell served on scientific advisory boards for Roche, Biogen, Novartis, Teva and Genzyme and has received conference travel support from Biogen and Novartis. His institution has received research support from Biogen, Merck and Novartis. Alessandra Lugaresi has served as a Biogen, Bristol Myers Squibb, Merck Serono, Novartis, Roche, Sanofi/Genzyme Advisory Board Member. She received congress and travel/accommodation expense compensations or speaker honoraria from Alexion, Biogen, Merck Serono, Novartis, Roche (2020), Sanofi/Genzyme, and Fondazione Italiana Sclerosi Multipla (FISM). Her institutions received research grants from Novartis and Sanofi/Genzyme.
: The AusImmune Study was approved by the Human Research Ethics Committee of the Australian National University. All 204 ROMS and 558 controls signed informed consent before participation. The PPMS Study was approved by Human Research Ethics Committee in Tasmania (H0014794) in 2015 and all 140 POMS participants provided signed consent forms. Waiver of consent by the AusImmune controls for the PPMS Study was approved by Human Research Ethics Committee of The Australian National University.