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Authors
Giannini, Giulia https://orcid.org/0000-0002-0499-3236
Baldelli, Luca https://orcid.org/0000-0003-3666-1735
Provini, Federica https://orcid.org/0000-0001-9063-2658
Cani, Ilaria https://orcid.org/0000-0002-9189-1982
Baiardi, Simone https://orcid.org/0000-0002-7702-7856
Sambati, Luisa https://orcid.org/0000-0002-5939-7933
Magliocchetti, Franco https://orcid.org/0009-0004-3894-8419
Guaraldi, Pietro https://orcid.org/0000-0003-0597-603X
Parchi, Piero https://orcid.org/0000-0002-9444-9524
Cortelli, Pietro https://orcid.org/0000-0002-3633-8818
Calandra-Buonaura, Giovanna https://orcid.org/0000-0002-9447-3532
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Funding
Funding for this research was provided by:
Ministero della Salute (Ricerca Corrente)
Alma Mater Studiorum - Università di Bologna
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Article History
Received: 27 December 2024
Revised: 8 February 2025
Accepted: 11 February 2025
First Online: 1 March 2025
Declarations
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: The authors declare that they have no conflict of interest.—Dr. Giannini reports no disclosures. Outside the present work, Dr. Giannini has received honoraria for speaking engagements or consulting activities from Bial;—Dr. Baldelli reports no disclosures.—Prof. Provini reports no disclosures. Outside the present work, Prof. Provini has received honoraria for speaking engagements or consulting activities from Italfarmaco, Idorsia, and Neopharmed Gentili S.p.A., and has received a grant from the Italian Ministry of Health (PNRR-MCNT2-2023–12377357);—Dr. Cani reports no disclosures. Outside the present work, Dr. Cani has received honoraria for speaking engagements or consulting activities from Bial;—Dr. Baiardi reports no disclosures.—Dr. Sambati reports no disclosures. Outside the present work, Dr. Sambati has received honoraria for speaking engagements or consulting activities from Bial and Roche;—Dr. Magliocchetti reports no disclosures.—Dr. Guaraldi reports no disclosures. Outside the present work, Dr. Guaraldi has received honoraria for speaking engagements or consulting activities from Alnylam;—Prof. Parchi reports no disclosures. Outside the present work, Prof. Parchi has received grants from the Italian Ministry of Health—PNRR 2023 (PNRR-MCNT2-2023–12378190) and from the EU Joint Program for Neurodegenerative Diseases (JPND, Transnational 2023 research call, Project Title: “Prionomics”);—Prof. Cortelli reports no disclosures. Outside the present work, Prof. Cortelli has received honoraria for speaking engagements or consulting activities from Jazz Pharmaceuticals, Abbvie, Zambon, Lundbeck;—Prof. Calandra-Buonaura reports no disclosures. Outside the present work, Prof. Calandra-Buonaura has received honoraria for speaking engagements or consulting activities from Bial.
: The study was conducted in agreement with the principles of good clinical practice. The study protocol was approved by the local ethics committee of the local health service of Bologna, Italy (Cod. CE: 09070 and 17093). All patients gave written informed consent for study participation.
