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Article History

Received: 20 April 2025

Revised: 29 May 2025

Accepted: 24 June 2025

First Online: 25 July 2025

Declarations

:

: L. Nüesch reports no disclosures relevant to the manuscript. K. Tisljar reports no disclosures relevant to the manuscript. S. Berger reports no disclosures relevant to the manuscript. G.M. De Marchis was or is supported by the Swiss National Science Foundation; Science Funds [Wissenschaftsfonds] of the University Hospital Basel and University of Basel; Bangerter-Rhyner-Stiftung; Swisslife Jubiläumsstiftung for Medical Research; Swiss Neurological Society; Fondazione Dr. Ettore Balli; De Quervain research grant; Thermo Fisher GmbH. He received travel honoraria by Bayer and speaker honoraria by Medtronic and BMS/Pfizer. T.D. Dittrich was or is supported by the Swiss Heart Foundation, the science funds of the University Hospital Basel, and the Research Fund for excellent young researchers of the University of Basel. He holds shares from Johnson & Johnson, Roche, Lilly, Bristol-Myers Squibb, Merck, and Novo Nordisk. S. Bassetti reports no disclosures relevant to the manuscript. R. Bingisser is editor of medstandards.com, a symptom-based medical decision-support tool licensed to 150 European hospitals, owned by the University Hospital Basel. S. Hunziker is supported by the Swiss National Foundation (SNF) (Ref 10001C_192850/1 and 10531C_182422), the Bangerter-Rhyner Foundation (8472/HEG-DSV), and the Swiss Society of General Internal Medicine (SSGIM). S. Marsch reports no disclosures relevant to the manuscript. R. Sutter received research grants from the Swiss National Foundation (No 320030_169379), the Research Fund of the University Basel, the Scientific Society Basel, and the Gottfried Julia Bangerter-Rhyner Foundation. He received personal grants from UCB-pharma and holds stocks from Alcon, Johnson & Johnson, Novartis, and Roche.

: The large language model (ChatGPT-4omni, OpenAI, San Francisco, USA) was used to paraphrase and summarize some of the manuscript’s content. After using this application, the authors further edited the content as needed and verified its accuracy.

: The study has been approved by the appropriate local ethics committee and have therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. All participants consented to participate in written form.