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Authors
Manini, Arianna https://orcid.org/0000-0003-3352-5228
Brusati, Alberto
Grassano, Maurizio
Scacciatella, Giulia
Peverelli, Silvia
Spagliardi, Jacopo
Pensato, Viviana
Doretti, Alberto
Vasta, Rosario
Manera, Umberto
Canosa, Antonio
Brunetti, Maura
Gentilini, Davide
Messina, Stefano
Verde, Federico
Moglia, Cristina
Morelli, Claudia
Dalla Bella, Eleonora
Keagle, Pamela J.
Landers, John E.
Gellera, Cinzia
Lauria Pinter, Giuseppe
Chiò, Adriano
Ratti, Antonia
Calvo, Andrea
Silani, Vincenzo https://orcid.org/0000-0002-7698-3854
Ticozzi, Nicola https://orcid.org/0000-0001-5963-7426
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Funding
Funding for this research was provided by:
Ministero della Salute (RF-2021-12374238, RF-2018-12367768)
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Article History
Received: 25 July 2025
Revised: 8 August 2025
Accepted: 10 August 2025
First Online: 22 August 2025
Declarations
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: VS received compensation for consulting services and/or speaking activities from AveXis, Cytokinetics, Italfarmaco, Liquidweb Srl, Novartis Pharma AG and Zambon Biotech SA. He is on the Editorial Board of Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, European Neurology, American Journal of Neurodegenerative Diseases, Frontiers in Neurology and Exploration of Neuroprotective Therapy. NT received compensation for consulting services from Amylyx Pharmaceuticals, Biogen, Italfarmaco and Zambon Biotech SA. He is Associate Editor for Frontiers in Aging Neuroscience. AD received compensation for consulting services and/or speaking activities from Abbvie, Eli Lilly, Teva, Lundbeck, Pfizer, IPSEN, Merz, Exeltis, Novartis, Zambon, Neopharmed Gentili, Piam.
: The study was approved by the Ethics Committee of the IRCCS Instituto Auxologico Italiano (2021_05_18) and by the Ethics Committee of the Turin ALS Center (Comitato Etico Azienda Ospedaliero-Universitaria Città della Salute e della Scienza, Torino). Written informed consent was obtained from each patient at the time of evaluation to use semi-anonymized clinical data for research purposes. The study was conducted in accordance with the principles of the Declaration of Helsinki.
