Sanchez van Kammen, Mayte https://orcid.org/0000-0001-5614-9689
Aaron, Sanjit
Ferreira, Jorge M. https://orcid.org/0000-0001-7138-7597
Canhão, Patrícia https://orcid.org/0000-0003-3816-0416
Conforto, Adriana B. https://orcid.org/0000-0001-7869-3490
Arauz, Antonio https://orcid.org/0000-0002-3340-4138
Carvalho, Marta https://orcid.org/0000-0001-6972-9287
Masjuan, Jaime https://orcid.org/0000-0003-1329-0943
Sharma, Vijay K. https://orcid.org/0000-0002-8976-5696
Putaala, Jukka https://orcid.org/0000-0002-6630-6104
Uyttenboogaart, Maarten https://orcid.org/0000-0002-6934-4456
Werring, David J. https://orcid.org/0000-0003-2074-1861
Bazan, Rodrigo https://orcid.org/0000-0003-3872-308X
Mohindra, Sandeep https://orcid.org/0000-0002-4629-4900
Weber, Jochen https://orcid.org/0009-0008-5891-4688
Coert, Bert A. https://orcid.org/0000-0003-3277-031X
Kirubakaran, Prabhu
Singh, Pankaj
Aguiar de Sousa, Diana https://orcid.org/0000-0002-6702-7924
Coutinho, Jonathan M. https://orcid.org/0000-0002-8284-982X
Ferro, José M. https://orcid.org/0000-0002-2343-9097
,
Funding for this research was provided by:
Jan Wouter ten Cate Prize (2021)
Article History
Received: 22 July 2025
Revised: 13 September 2025
Accepted: 18 September 2025
First Online: 10 October 2025
Declarations
:
: Dr Uyttenboogaart reports grants from Hartstichting and ZonMw. Dr Werring reports grant funding from the Stroke Association and British Heart Foundation, speaking honoraria from Bayer, speaking and chairing honoraria from Alexion and NovoNordisk, and consultancy fees from Alnylam, Bayer, and NovoNordisk. Dr Aguiar de Sousa reports personal fees for AstraZeneca, Organon, and Johnson & Johnson advisory board participation, DSMB participation for the SECRET trial (University of British Columbia), and speaking fees from Astrazeneca and Bial. Dr Coutinho reports grants paid to his institution from Boehringer Ingelheim and Bayer. Dr Ferro reports personal fees from Bayer. The other authors report no conflicts of interest.
: This study was performed in line with the principles of the Declaration of Helsinki. Approval was obtained from the ethics committee of Hospital de Santa Maria in Lisbon, Portugal.
: Informed consent for the use of pseudonymized care data was obtained if required according to local laws and regulations.