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Authors
Matsuda, Chiharu https://orcid.org/0000-0001-9209-6094
Nakayama, Yuki https://orcid.org/0000-0001-8620-612X
Haraguchi, Michiko https://orcid.org/0009-0002-8520-4338
Morishima, Ryo https://orcid.org/0000-0003-0774-2827
Itagaki, Yumi https://orcid.org/0000-0002-1439-0017
Bokuda, Kota https://orcid.org/0000-0002-8577-6654
Hayashi, Kentaro https://orcid.org/0000-0001-7124-7658
Takahashi, Kazushi https://orcid.org/0000-0003-2904-6080
Shimizu, Toshio https://orcid.org/0000-0002-3828-9669
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Funding
Funding for this research was provided by:
Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research [B] No. 23K24656)
Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research[C] No. 23K09948)
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Article History
Received: 24 January 2026
Revised: 14 March 2026
Accepted: 17 March 2026
First Online: 11 April 2026
Declarations
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: The authors have no competing interests to declare that are relevant to the content of this article.
: The study was approved by the Ethics Committee of the Tokyo Metropolitan Institute of Medical Science (Approval Nos. 22–19 and 23–17). Informed consent was obtained via an opt-out procedure. The study adhered to the latest version of the Declaration of Helsinki and complied with the Ethical Guidelines for Medical and Health Research Involving Human Subjects of Tokyo Metropolitan Institute of Medical Science and the Ethical Guidelines for Clinical Research of Tokyo Metropolitan Neurological Hospital.
