Fragiotta, Serena https://orcid.org/0000-0002-6214-6270
Parravano, Mariacristina https://orcid.org/0000-0002-2223-7311
Costanzo, Eliana https://orcid.org/0000-0002-9916-8895
De Geronimo, Daniele https://orcid.org/0000-0003-3242-8020
Varano, Monica https://orcid.org/0000-0002-6530-1563
Borrelli, Enrico https://orcid.org/0000-0003-2815-5031
Barresi, Costanza https://orcid.org/0000-0003-4828-7170
Sacconi, Riccardo https://orcid.org/0000-0003-2891-2012
Querques, Giuseppe https://orcid.org/0000-0002-3292-9581
Funding for this research was provided by:
Ministero della Salute
Fondazione Roma
Article History
Received: 16 February 2025
Revised: 20 October 2025
Accepted: 24 October 2025
First Online: 12 November 2025
Declarations
:
: All procedures performed in studies involving human participants were in accordance with the ethical standards of the IRCCS-Bietti Foundation, Rome (IT) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
: Informed consent was obtained from all individual participants included in the study.
: S. Fragiotta has received a speaker honorarium from Bayer. M. Parravano has received personal fees as speaker and consultant from Abbvie, Novartis, Bayer, Zeiss, Omikron, Alfaintes, Sifi. M. Varano has received a speaker and consultant honorarium from Abbvie, Novartis, Bayer, Sifi. E. Borrelli, reports personal feed from Abbvie, Bayer, Hofmann La Roche, Zeiss; R. Sacconi has received a speaker and consultant honorarium from Novartis, Bayer, Zeiss. G. Querques has received a speaker and consultant honorarium from Alimera Sciences, Inc; Allegro, Abbvie, Apellis, Baush & Lomb, Bayer Healthcare Pharmaceuticals, Boehringer Ingelheim, CenterVue, Heidelberg Engineering, Lumithera, Nevacar, Novartis Pharmaceuticals Corporation, Roche, SIFI, Sooft/Fidia, Topcon, Thea, Zeiss. All the personal fees reported are outside the submitted work.The remaining authors have no proprietary/financial interest or non-financial interest in the subject matter or materials discussed in this manuscript.