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Article History

Received: 17 December 2025

Revised: 12 March 2026

Accepted: 5 April 2026

First Online: 16 April 2026

Declarations

:

: This study was performed according to the Declaration of Helsinki. Tissue samples originated from routine therapeutic surgeries, for all of which the patients had given written informed consent. Ethical approval was obtained from the local ethical review board (D 453/10 and D 525/15) of the University Hospital Schleswig–Holstein, Kiel, Germany, which permitted us to use the samples from those patients, who had also given written informed consent for a prospective scientific use of their patient material. After study inclusion, data from all patients was pseudonymized.

: Not applicable.

: The authors declare no conflict of interest.