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Isohemagglutinins exhibit synergistic polyreactivity toward Streptococcus pneumoniae surface antigens: implications for broad-spectrum reactivity of human antibodies

Crossref DOI link: https://doi.org/10.1007/s00430-025-00862-y

Published Online: 2026-01-09

Published Print: 2026-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Bernth Jensen, Jens Magnus https://orcid.org/0000-0002-5004-7822
Søgaard, Ole Schmeltz https://orcid.org/0000-0001-9107-2023
Petersen, Mikkel Steen https://orcid.org/0009-0002-6317-553X
Hoffmann, Steen

Møller, Bjarne Kuno https://orcid.org/0000-0003-2808-4755
Hansen, Annette Gudmann

Sørensen, Uffe B. Skov https://orcid.org/0000-0002-6777-054X
Thiel, Steffen https://orcid.org/0000-0002-4817-155X
Funding

Funding for this research was provided by:

Aarhus University Hospital
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Text and Data Mining valid from 2026-01-09

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Article History

Received: 1 June 2025

Accepted: 25 October 2025

First Online: 9 January 2026

Declarations

:

: The authors declare no competing interests.

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