Kruger, Dinja T.
Opdam, Mark
van der Noort, Vincent
Sanders, Joyce
Nieuwenhuis, Michiel
de Valk, Bart
Beelen, Karin J.
Linn, Sabine C.
Boven, Epie http://orcid.org/0000-0001-9287-743X
Funding for this research was provided by:
Novartis Pharma
Article History
Received: 21 May 2020
Accepted: 12 June 2020
First Online: 21 June 2020
Compliance with ethical standards
:
: DTK declares that she has no conflict of interest. MO declares that he has no conflict of interest. VvdN declares that he has no conflict of interest. JS declares that she has no conflict of interest. MN declares that he has no conflict of interest. BdV declares that he has no conflict of interest. KJB declares that she has no conflict of interest. SCL is an advisory board member for AstraZeneca, Cergentis, Novartis, Roche and Sanofi. SCL received institutional research support funding from Adienne, Agendia, Amgen, AstraZeneca, Genentech, Immunomedics, Roche, Tesaro and Sanofi. EB declares that she has no conflict of interest.
: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The study was approved by the Independent Ethics Committee of Amsterdam UMC and Institutional Review Board at each participating site. The study was performed in compliance with Good Clinical Practices and carried out in keeping with applicable local law(s) and regulation(s).
: All patients signed informed consent before enrolment which included, among others, recording the efficacy of treatment, if possible a non-osseous tumour biopsy at baseline and the retrieval of archival primary tumour tissue.
: Novartis Pharma BV reviewed the manuscript for medical accuracy only before journal submission. The authors are fully responsible for the contents of this manuscript, and the views and opinions described in the publication reflect solely those of the authors. All authors have agreed to submission of the data.