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Article History

Received: 24 June 2023

Accepted: 4 August 2023

First Online: 16 August 2023

Declarations

:

: The authors have no relevant financial or non-financial interests to disclose.

: All the procedures involving human participants performed in this study were in accordance with the ethical standards of the Kyushu University Ethics Committee (study approval numbers 29-251) and the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. All animal procedures were performed in accordance with the ethical standards of the Animal Care and Use Committee of Kyushu University (study approval number: A22-278-0).

: Written informed consent was obtained from all the participants included in the study for the use of their PBMC and tumor specimen for research and for publication before blood collection.

: Written informed consent was obtained from all participants included in the study for the use of their PBMC and tumor specimen for research and for publication before blood collection.

: All mice were obtained from Charles River Laboratories Japan (Yokohama, Japan).

: SBC5 cell line was obtained from the Japanese Collection of Research Bioresources bank. The Sq-1 cell line was purchased from Riken Bio Resource Research Center. All cell lines were cultured for no more than 2–3 weeks after thawing, routinely checked for mycoplasma infection, and showed consistent phenotypes by microscopy prior to the in vitro and in vivo experiments.