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In vitro analysis of the activities of commercial anthelmintics in the presence of inhibitors of xenobiotic detoxification pathways in Haemonchus contortus exsheathed L3 stage

Crossref DOI link: https://doi.org/10.1007/s00436-025-08468-2

Published Online: 2025-02-20

Published Print: 2025-02

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Nieves, Magdalena

Duarte, Gerardo

Saldaña, Jenny

Melian, María Elisa

Munguía, Beatriz
Funding

Funding for this research was provided by:

Programa de Desarrollo de Ciencias Básicas

CSIC – Udelar for the Posgraduate scholarship (BDMX_2023_1#49499052)

Comisión Sectorial de Investigación Científica de la Universidad de la República (Research project 366)

Comisión Sectorial de Investigación Científica de la Universidad de la República (Research project 366)

Comisión Sectorial de Investigación Científica de la Universidad de la República (Research project 366)
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Article History

Received: 20 August 2024

Accepted: 10 February 2025

First Online: 20 February 2025

Declarations

:

: Artificial infection in sheep with third stage larvae (L3) of H. contortus from the anthelmintic-susceptible McMaster isolate (Kirby) was maintained at a private farm called “Se puede,” at Empalme Olmos, Uruguay, as we have previously described (Munguía et al. ). The animal protocol complied with Uruguayan Law No. 18.611. Experimental protocol was reviewed and approved for this study by IACUC of Facultad de Química – Udelar, Uruguay (file N° 101900–500053-21).

: Not applicable.

: The authors declare no competing interests.

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