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Authors
Sassoli, Chiara https://orcid.org/0000-0002-1337-0938
Vallone, Larissa
Tani, Alessia
Chellini, Flaminia
Nosi, Daniele
Zecchi-Orlandini, Sandra
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Article History
Received: 27 July 2017
Accepted: 6 January 2018
First Online: 5 February 2018
Compliance with ethical standards
:
: The authors declare that they have no conflict of interest.
: All procedures performed in studies involving animals were in accordance with the European Community guidelines for animal care (DL 116/92, application of the European Communities Council Directive of 24 November 1986; 86/609/EEC) and approved by the Committee for Animal Care and Experimental Use of the University of Florence - No. A5278–01. The protocols were communicated to local authorities and to the Italian Ministry of the Health; according to Italian law (Art.7/D.lgs 116/92) such a procedure does not require Ministry authorization. PRP was obtained at the Immunohaematology and Transfusion Medicine Unit of the University Hospital of Careggi (Florence) from the whole blood of adult healthy volunteers after receiving an informed consent and was provided in ready-to-use aliquots classified as not suitable for transfusion-infusion purposes. Its use in experimental in vitro protocols does not require Ethical Committee’s approval.
