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Authors
Ebina, Koki https://orcid.org/0000-0002-4452-4274
Abe, Takashige https://orcid.org/0000-0002-5468-7632
Hotta, Kiyohiko
Lingbo, Yan
Kamijo, Chihiro
Higuchi, Madoka
Kon, Masafumi
Kikuchi, Hiroshi
Miyata, Haruka
Matsumoto, Ryuji
Osawa, Takahiro
Murai, Sachiyo
Senoo, Taku
Komizunai, Shunsuke
Tsujita, Teppei
Sase, Kazuya
Chen, Xiaoshuai
Konno, Atsushi
Shinohara, Nobuo
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Funding
Funding for this research was provided by:
Japan Society for the Promotion of Science (JP17K08897, JP18H04102, JP21H00893, JP23H00480, JP24K00443, JP23K18486, JP22KJ0118)
Japan Agency for Medical Research and Development (JP22vk0124006)
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Article History
Received: 1 May 2025
Accepted: 13 July 2025
First Online: 26 July 2025
Declarations
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: Drs. Koki Ebina, Takashige Abe, Kiyohiko Hotta, Yan Lingbo, Chihiro Kamijo, Madoka Higuchi, Masafumi Kon, Hiroshi Kikuchi, Haruka Miyata, Ryuji Matsumoto, Takahiro Osawa, Sachiyo Murai, Taku Senoo, Shunsuke Komizunai, Teppei Tsujita, Kazuya Sase, Xiaoshuai Chen, Atsushi Konno, and Nobuo Shinohara have no conflicts of interest or financial ties to disclose.
: This study was approved by the Ethical Review Board for Life Science and Medical Research of Hokkaido University Hospital (No. 018–0257). All procedures performed in studies involving human participants were in accordance with the ethical standards of the Institutional Research Committee and the Declaration of Helsinki of 1964 and its subsequent amendments or comparable ethical standards.
