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Authors
Hasegawa, Takumi
Etoh, Tsuyoshi
Nakano, Tomoki
Aoyama, Yoshimasa
Matsunobu, Yusuke
Fujishima, Reo
Fujita, Shunsuke
Shitomi, Yuki
Akagi, Tomonori
Ninomiya, Shigeo
Ueda, Yoshitake
Tokuyasu, Tatsushi
Inomata, Masafumi
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Funding
Funding for this research was provided by:
Olympus
Japan Society for the Promotion of Science (JP24K11851)
Oita University
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Article History
Received: 8 April 2026
Accepted: 5 June 2026
First Online: 1 July 2026
Declarations
Disclosures: Yoshimasa Aoyama received a grant from the Japan Society for the Promotion of Science (JSPS KAKENHI Grant Number JP24K11851). Masafumi Inomata received research funding from Olympus Corporation for collaborative work. Olympus Corporation had no role in the study design, data analysis, interpretation, or manuscript preparation. Takumi Hasegawa, Tsuyoshi Etoh, Tomoki Nakano, Yusuke Matsunobu, Reo Fujishima, Syunsuke Fujita, Yuki Shitomi, Tomonori Akagi, Shigeo Ninomiya, Yoshitake Ueda, and Tatsushi Tokuyasu have no conflicts of interest or financial ties to disclose.
Ethical approval: The protocol for this research project has been approved by a suitably constituted Ethics Committee of the institution and it conforms to the provisions of the Declaration of Helsinki. Approval was granted by the Oita University Faculty of Medicine Ethics Committee (approval number: 2772-D25) and the institutional review boards of all participating institutions. The trial was registered in the UMIN Clinical Trials Registry (UMIN000052901). An opt-out approach was used to obtain informed consent from patients, allowing them to refuse participation.
