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Article History

Received: 9 August 2018

Accepted: 23 April 2019

First Online: 15 May 2019

Compliance with ethical standards

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: Gilles Allano reports non-financial support from Kyowa Kirin, during the conduct of the submitted work; personal fees and non-financial support from Grunenthal, Mundipharma, and Medtronic, and non-financial support from Kyowa Kirin, outside the submitted work. Brigitte George reports non-financial support from Kyowa Kirin, during the conduct of the submitted work; personal fees and non-financial support from Mundipharma, non-financial support from Grunenthal and Kyowa Kirin, outside the submitted work; participation to a clinical study without honoraria from Bouchara. Christian Minello reports non-financial support from Kyowa Kirin, during the conduct of the submitted work; personal fees and non-financial support from Takeda, and non-financial support from Kyowa Kirin, Mundi Pharma, Mylan Pharma, and Grunenthal, outside the submitted work. Alexis Burnod reports non-financial support from Kyowa Kirin, during the conduct of the submitted work; non-financial support from Kyowa Kirin, outside the submitted work. Caroline Maindet reports non-financial support from Kyowa Kirin, during the conduct of the submitted work; personal fees and non-financial support from Mundipharma, and non-financial support from Kyowa Kirin, Grunenthal, Hospira, Takeda, and Janssen Cilag, outside the submitted work. Antoine Lemaire reports non-financial support from Kyowa Kirin France, during the conduct of the submitted work; personal fees and non-financial support from Kyowa Kirin International, Mundi Pharma, Grunenthal and Takeda; personal fees from Mylan, and non-financial support from Kyowa Kirin France, Archimèdes Pharma, Teva, and Prostrakan, outside the submitted work.