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Authors
Wang, Meng
Wen, Xing
Yang, Mei
Zhang, Jie
Gu, Jianhui
Lu, Tianqi https://orcid.org/0000-0003-0898-2195
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Funding
Funding for this research was provided by:
Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Würzburg (CSY-YN-01-2023-009)
The Third People’s Hospital of Chengdu Scientific Research Project (2023PI27)
National Natural Science Foundation of China (82303723)
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Article History
Received: 4 January 2026
Accepted: 6 May 2026
First Online: 27 May 2026
Declarations
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: The authors have no relevant financial or non-financial interests to disclose.
: This study was performed in line with the principles of the Declaration of Helsinki. Cancer and paracancerous tissue samples from CRC patients were collected after informed consent of the patients and approval by the Ethics Committee of the Third People’s Hospital of Chengdu (Ethics of Chengdu Third Hospital 2025-S-263). All animal experiments were conducted in accordance with the guidelines of the ethics committee and approved by Experimental Animal Welfare and Ethics Committee of Wuhan Whupenn life science Co., Ltd (LBSM2025013).
