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Polyherbal formulation mitigates high-fat diet-induced hepatic steatosis by targeting insulin resistance, hepatic lipid accumulation, and oxidative stress via modulation of the two-hit hypothesis

Crossref DOI link: https://doi.org/10.1007/s00580-025-03732-4

Published Online: 2025-12-09

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Chandrasekharnath, N.

Uma, A.

Mahalakshmi, Y. V.
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Text and Data Mining valid from 2025-12-09

Version of Record valid from 2025-12-09
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Article History

Received: 19 July 2025

Accepted: 29 October 2025

First Online: 9 December 2025

Declarations

:

: The animal experiments protocol was approved by the Institutional Animal Ethics Committee (IAEC) of Jeeva Life Sciences, Hyderabad, Telangana, India (Approval No: CCSEA/IAEC/JLS/21/04/24/042) and all animal experiments were conducted according to the guidelines of Committee for Control and Supervision of Experiments on Animals (CCSEA), Government of India. No human participants were involved in this study.

: Not applicable.

: Not applicable.

: The authors declare no competing interests.

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