Özcan Ekşi, Emel Ece
Ekşi, Murat Şakir
Article History
Received: 15 June 2025
Revised: 9 July 2025
Accepted: 13 July 2025
First Online: 21 July 2025
Declarations
:
: Authors declare that they have no conflict of interest related to the current study content. Murat Şakir EKŞİ, M.D., is an academic consultant for Karmed & Biobone and receives an honorarium from Elsevier.
: was not required for the first component of the study (systematic review), as all data used were publicly available and anonymized. Informed consent was waived for this part of the study by the Institutional Review Board.The second part of the study was approved by the Institutional Review Board (FSMEAH-KAEK 2023/33) and conducted in accordance with the Declaration of Helsinki and its later amendments. Written informed consent was obtained from all participants and control subjects.