Document is current

Article History

Received: 22 October 2025

Accepted: 6 December 2025

First Online: 27 December 2025

Declarations

:

: All the studies implying research work applied to biological samples (human blood, plasma, and/or serum) were conducted in accordance with the Declaration of Helsinki, and the aforementioned projects and, consequently, the present study, in accordance with the Spanish regulation ‘Real Decreto 1090/2015, de 4 de diciembre, por el que se regulan los ensayos clínicos con medicamentos, los Comités de Ética de la Investigación con medicamentos y el Registro Español de Estudios Clínicos’, was approved by the Research Ethics Committee of Cadiz (Spain), on May 12, 2023, registry/protocol number 15.23. The resolution stated that the aforementioned projects, involving human samples, are viable, that they present sufficient methodological rigor, that the evaluation of economic costs are correct, and that with respect to the ethical aspects, the projects meet the necessary requirements of suitability of the protocol in relation to the objectives of the study.

: Not applicable.

: The authors declare no competing interests.