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Centrifugal pipette-tip extraction using pyrolyzed cotton fibers combined with mass spectrometry: High-throughput analysis of methadone and its major metabolite in human urine

Crossref DOI link: https://doi.org/10.1007/s00604-026-07937-4

Published Online: 2026-02-26

Published Print: 2026-03

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Millán-Santiago, Jaime

Lucena, Rafael

Cárdenas, Soledad
Funding

Funding for this research was provided by:

Universidad de Córdoba
License Information

Text and Data Mining valid from 2026-02-26

Version of Record valid from 2026-02-26
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Article History

Received: 28 November 2025

Accepted: 14 February 2026

First Online: 26 February 2026

Declarations

:

: All experiments were performed in accordance with the Helsinki declaration and were approved by the Research Ethics Committee of the Province of Cordoba (SICEIA-2023–000030) accredited body that depends on the Andalusian Health Service (Regional Government of Andalucia). Each volunteer provided written informed consent to participate in this study following the guidelines established by the regulators (Real Decreto 1716/2011).

: The authors declare no competing interests.

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