Eide, Per Kristian https://orcid.org/0000-0001-6881-9280
Hovd, Markus https://orcid.org/0000-0002-6077-0934
Valnes, Lars Magnus https://orcid.org/0000-0001-9283-5563
Pripp, Are https://orcid.org/0000-0002-1678-7309
Ringstad, Geir https://orcid.org/0000-0003-0919-4510
Funding for this research was provided by:
Stiftelsen Kristian Gerhard Jebsen
University of Oslo
Article History
Received: 2 November 2025
Accepted: 18 December 2025
First Online: 5 January 2026
Declarations
:
: Ethical standards in line with the Declaration of Helsinki (1975, revised in 1983) were strictly followed. The study employed a prospective and observational design.
: Approvals for this study were obtained from the following authorities: i) The Institutional Review Board of Oslo University Hospital (2015/1868). ii) The Regional Committee for Medical and Health Research Ethics (REK) of Health Region South-East, Norway (2015/96). iii) The Norwegian Medicines Agency (15/04932–7). The study was registered in the Oslo University Hospital Research Registry (ePhorte 2015/1868).
: Patients were included after oral- and written informed consent.
: Not applicable.
: The authors declare no competing interests.