Marchioni, Camila
Santos-Lobato, Bruno Lopes
Queiroz, Maria Eugênia Costa
Crippa, José Alexandre S.
Tumas, Vitor http://orcid.org/0000-0003-2402-2709
Funding for this research was provided by:
Fundação de Amparo à Pesquisa do Estado de São Paulo (159688/2015-9)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (2012/17626-7)
Article History
Received: 28 June 2020
Accepted: 5 August 2020
First Online: 14 August 2020
Compliance with ethical standards
:
: Dr. CRIPPA is co-inventor (Mechoulam R, Zuardi AW, Kapczinski F, Hallak JEC, Guimarães FS, Crippa JA, Breuer A) of the patent ‘Fluorinated CBD compounds, compositions and uses thereof. Pub. No.: WO/2014/108,899. International Application No.: PCT/IL2014/050,023′, Def. US no. Reg. 62,193,296; 29/07/2015; INPI on 19/08/2015 (BR1120150164927). The University of São Paulo has licensed the patent to Phytecs Pharm (USP Resolution No. 15.1.130002.1.1). The University of São Paulo has an agreement with Prati-Donaduzzi (Toledo, Brazil) to ‘develop a pharmaceutical product containing synthetic cannabidiol and prove its safety and therapeutic efficacy in the treatment of epilepsy, schizophrenia, Parkinson’s disease, and anxiety disorders’. Dr. CRIPPA has received travel support from BSPG-Pharm and is a medical advisor of SCBD Centre. Dr. CRIPPA has a grant from University Global Partnership Network (UGPN)–Global priorities in cannabinoid research excellence. Dr. CRIPPA is a member of the international advisory board of the Australian Centre for Cannabinoid Clinical and Research Excellence (ACRE), funded by the National Health and Medical Research Council through the Centre of Research Excellence. Dr. CRIPPA is recipient of CNPq 1A productivity fellowship. Dr. TUMAS received honoraria from Teva Brasil, UCB Biopharma and Ipsen, and travel support for medical conferences from Roche.
: The study was approved by institutional review board of the Ribeirão Preto Medical School (Number 3.036.243), and each participant provided written informed consent to participate.
: Authors declare that informed consents for participation were obtained from all participants. Moreover, informed consents for lumbar pucture examination were also obtained from all participants.
: Authors declare that consent for publication of blinded data was a part of informed consents obtained from participants.