Crossmark

Association between deletions in the preS1/2 region of the hepatitis B virus genome and persistently abnormal ALT levels in patients with chronic hepatitis B treated with nucleos(t)ide analogs

Crossref DOI link: https://doi.org/10.1007/s00705-025-06480-6

Published Online: 2025-12-18

Published Print: 2026-01

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Sato, Yurina

Doi, Kotaro

Inoue, Jun https://orcid.org/0000-0003-1171-7835
Ninomiya, Masashi

Tsuruoka, Mio

Sato, Kosuke

Onuki, Masazumi

Sawahashi, Satoko

Ouchi, Keishi

Watanabe, Kengo

Niitsuma, Hirofumi

Masamune, Atsushi
Funding

Funding for this research was provided by:

Japan Society for the Promotion of Science (23K07390)
License Information

Text and Data Mining valid from 2025-12-18

Version of Record valid from 2025-12-18
More Information

Article History

Received: 6 May 2025

Accepted: 1 September 2025

First Online: 18 December 2025

Declarations

:

: The authors have no relevant financial or non-financial interests to disclose.

: This study was approved by the medical ethics committee of Tohoku University (approval numbers 2016-1-280, 2020-1-1106, and 2024-1-012).

Document is current

Any future updates will be listed below